Dietas experimentais hiperlipídicas e compostos bioativos com efeito hipolipêmico
Resumo
Introdução: Dietas experimentais hiperlipídicas são modelos úteis para avaliar os impactos fisiológicos de dietas ricas em gorduras em humanos, assim como para avaliar impacto de compostos bioativos sobre estas condições. Assim, o objetivo deste estudo é identificar os modelos de dietas experimentais hiperlipídicas apresentados pela literatura e verificar os compostos bioativos utilizados para atenuação dos efeitos promovidos por estas dietas. Materiais Métodos: Foi realizada uma revisão de literatura, onde foram utilizadas as bases de dados “Google acadêmico”, “Pubmed”, “Scielo” e “Cochrane”. As palavras-chave utilizadas na busca foram “High fat diet” e “Hyperlipidic diet”. Resultados: Os resultados mostraram que os modelos de dieta hiperlipídica apresentaram importante variação em relação aos teores de lipídios utilizados, bem como em relação aos componentes lipídicos empregados. Também se verificou grande variabilidade em relação aos compostos bioativos testados para atenuar os efeitos destas dietas, sendo que estes compostos podem ser obtidos de frutas, temperos, cogumelos e uma grande variedade de plantas. Conclusão: Portanto, os modelos de dietas experimentais hiperlipídicas não apresentam padronização o que dificulta a interpretação e comparação de diferentes resultados.
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