Hyperlipid experimental diets and bioactive compounds with hypolipemic effect
Abstract
Introduction: Experimental high-fat diets are useful models for assessing the physiological impacts of high-fat diets on humans, as well as, for assessing the impacts of bioactive compounds on these conditions. Thus, the objective of this study is to identify the models of experimental high-fat diets presented by the literature and to verify the bioactive compounds used to attenuate the effects promoted by these diets. Materials and Methods: A literature review was carried out, using the databases "Google academic", "Pubmed", "Scielo" and "Cochrane". The keywords used in the search were “High fat diet” and “Hyperlipidic diet”. Results: The results showed that the high-fat diet models showed an important variation in relation to the levels of lipids used, as well as in relation to the lipid components used. There was also great variability in relation to the bioactive compounds tested to mitigate the effects of these diets, these compounds being obtained from fruits, spices, mushrooms and a wide variety of plants. Conclusion: Therefore, the models of experimental high-fat diets do not present standardization, which makes it difficult to interpret and compare different results.
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