What are the benefits of physical activity in patients with breast cancer on physical and psychological health? A systematic review of randomized clinical trials

  • Lailton Oliveira da Silva Universidade Federal do Ceará-UFC, Brasil.
  • Ismenia Martineli Lima de Sousa Universidade Estadual do Ceará-UECE, Brasil.
  • Raquel Texeira Terceiro Paim UNIFAMETRO, Brasil.
  • Anderson Weiny Bardalho Filho Universidade Federal do Ceará-UFC, Brasil.
  • José Juvenal Linhares Universidade Federal do Ceará-UFC, Brasil.
Keywords: Breast Neoplasms, Physical activity, Physical exercise

Abstract

Introduction: Breast cancer (BC) is a worldwide public health problem that affects women's body image and sexuality. Physical exercise has been considered one of the significant and effective non-pharmacological strategies to minimize physical and psychological consequences. Objective: To identify and describe the scientific evidence on the interventions of physical exercises in the physical and psychological health of individuals with BC. Materials and Methods: A systematic review was performed blindly and independently, from December 2022 to January 2023, according to PRISMA guidelines. The results were obtained by direct online access through the databases: PubMed, Science Direct and Capes, using the combination of the following descriptors in English: Breast Neoplasms, Physical activity, and Physical exercise. Results and Discussion: A total of 17 studies were selected, with a sample of 2,091 participants with an average age of 53 years. The studies included aerobic, resistance, stretching, and strengthening exercises. Although combined exercises result in better overall quality of life, anxiety, depression and muscle strength indices, resistance exercises alone also promote good results for this population. Conclusion: Patients with BC can benefit from the practice of physical exercises, improving aspects related to general physical and psychological health. This study can still contribute with new works considering the minimally described information about which types of interventions can be applied for an effective result. It is recommended that more randomized clinical trials be performed to obtain more concise results.

References

-Abed, J.; Dolan, L.; Jones, J.; Dinniwell, R. Impact of self-reported exercise on recounted levels of fatigue and anxiety in early-stage breast cancer radiation therapy patients. Journal of Medical Imaging and Radiation Sciences. Vol. 50. Num. 2. p. 227-233. 2019.

-Ammitzboll, G.; Andersen, K.G.; Bidstrup, P. E.; Johansen, C.; Lanng, C.; Kroman, N.; Zerahn, B.; Hyldegaard, O.; Andersen, E. W.; Dalton, S. O. Effect of progressive resistance training on health-related quality of life in the first year after breast cancer surgery-results from a randomized controlled trial. Acta oncológica. Vol. 58. Num. 5. p. 665-672. 2020.

-Ariza-Garcia, A.; Lozano-Lozano, M.; Galiano-Castillo, N.; Postigo-Martin, P.; Arroyo-Morales, M.; Cantarero-Villanueva, I. A web-based exercise system (e-CuidateChemo) to counter the side effects of chemotherapy in patients with breast cancer: randomized controlled trial. Journal of medical Internet Research. Vol. 21. Num. 7. p. e14418. 2019.

-Bascha, M. A.; Aboelnour, N. H.; Alsharidah, A. S.; Kamel, F. H. Effect of exercise mode on physical function and quality of life in breast cancer–related lymphedema: a randomized trial. Supportive Care in Cancer. Vol. 30. Num. 3. p. 2101-2110. 2022.

-Bezerra, A. S.; Oliveira, T. A. A importância da atividade física no tratamento do câncer de mama. Revista Brasileira de Prescrição e Fisiologia do Exercício. São Paulo. Vol. 13. Num. 87. p. 1292-1298. 2019.

-Cannioto, R. A.; Hutson, A.; Dighe, S.; McCann, W.; McCann, S.; Zirpoli, G. R.; Barlow, W.; Kelly, K. M.; DeNysschen, C. A.; Hershman, D. L.; Unger, J. M.; Moore, H. C. F.; Stewart, J. A.; Isaacs, C.; Hobday, T. J.; Salim, M.; Hortobagyi, G. N.; Gralow, J. R.; Albain, K. S.; Budd, G. T.; Ambrosone, C. B.; Physical activity before, during, and after chemotherapy for high-risk breast cancer: relationships with survival. Journal of the National Cancer Institute. Vol. 113. Num. 1. p. 54-63. 2021.

-Carayol, M.; Ninot, G.; Senesse, P.; Bleuse, J. P.; Gourgou, S.; Sancho-Garnier, H.; Sari, C.; Romieu, I.; Romieu, G.; Jacot, W.; Short-and long-term impact of adapted physical activity and diet counseling during adjuvant breast cancer therapy: the “APAD1” randomized controlled trial. BMC câncer. Vol. 19. Num. 1. p. 1-20. 2019.

-Carvalho, A. S.; Passos, R. P.; Pereira, A. A.; Carvalho, A. F.; Martelli, A.; Lima, B. N.; Martins, G. C.; Oliveira, H. F.R.; Oliveira, J. R.; L.; Almeida, K. S.; Silio, L. F.; Rodrigues, M. F.; Maneschy, M. S.; Guedes, U. I. S.; Fileni, C. H. P.; Abdalla, P. P.; Vilela Junior, G. B. Exercício físico: aliado para o tratamento de pessoas com câncer. Revista Centro de Pesquisas Avançadas em Qualidade de Vida. Vol. 14. Num. 1. p. 2. 2022.

-Cešeiko, R.; Thomsen, S. N.; Tomsone, S.; Eglītis, J.; Vētra, A.; Srebnijs, A.; Timofejevs, M.; Purmalis, E.; Wang, E. Heavy resistance training in breast cancer patients undergoing adjuvant therapy. Medicine & Science in Sports & Exercise. Vol. 52. Num. 6. p. 1239-1247. 2020.

-Cešeiko, R.; Eglītis, J.; Srebnijs, A.; Timofejevs, M.; Purmalis, E.; Erts, R.; Vētra, A.; Tomsone, S. The impact of maximal strength training on quality of life among women with breast cancer undergoing treatment. Exp Oncol. Vol. 41. Num. 2. p. 166-72. 2019.

-Deli-Conwright, C. M.; Courneya, K. S.; Demark-Wahnefried, W.; Sami, N.; Lee, K.; Sweeney, F. C.; Stewart, C.; Buchanan, T. A.; Spicer, D.; Tripathy, D.; Bernstein, L.; Mortimer, J. E. Aerobic and resistance exercise improves physical fitness, bone health, and quality of life in overweight and obese breast cancer survivors: a randomized controlled trial. Breast Cancer Research. Vol. 20. Num. 1. p. 1-10. 2018.

-Dong, X.; Yi, X.; Gao, D.; Gao, Z.; Huang, S.; Chao, M.; Chen, W.; Ding, M. The effects of the combined exercise intervention based on internet and social media software (CEIBISMS) on quality of life, muscle strength and cardiorespiratory capacity in Chinese postoperative breast cancer patients: a randomized controlled trial. Health and Quality of Life Outcomes. Vol. 17. Num. 1. p. 1-9. 2019.

-García-Soidán, J. L.; Pérez-Ribao, I.; Leirós-Rodríguez, R.; Soto-Rodríguez, A.; Long-term influence of the practice of physical activity on the self-perceived quality of life of women with breast cancer: a randomized controlled trial. International Journal of Environmental Research and Public Health. Vol. 17. Num. 14. p. 4986. 2020.

-Hartman, S. J.; Weiner, L. S.; Nelson, S. H.; Natarajan, L.; Patterson, R. E.; Palmer, B. W.; Parker, B. A.; Sears, D.D.; Mediators of a physical activity intervention on cognition in breast cancer survivors: Evidence from a randomized controlled trial. JMIR câncer. Vol. 5. Num. 2. p. e13150. 2019.

-Hazard-Jenkins, H. W. Breast Cancer Survivorship-Mitigating Treatment Effects on Quality of Life and Improving Survival. Obstetrics and Gynecology Clinics. Vol. 49. Num. 1. p. 209-218. 2022.

-Jia, T.; Liu, Y.; Fan, Y.; Wang, L.; Jiang, E. Association of Healthy Diet and Physical Activity With Breast Cancer: Lifestyle Interventions and Oncology Education. Frontiers in Public Health. Vol. 10. 2022.

-Mijwel, S.; Backman, M.; Bolam, K. A.; Jervaeus, A.; Sundberg, C. J.; Margolin, S.; Browall, M.; Rundqvist, H.; Wengström, Y.; Adding high-intensity interval training to conventional training modalities: optimizing health-related outcomes during chemotherapy for breast cancer: the OptiTrain randomized controlled trial. Breast cancer research and Treatment. Vol. 168. Num. 1. p. 79-93. 2018.

-Mijwel, S.; Backman, M.; Bolam, K. A.; Olofsson, E.; Norrbom, J.; Bergh, J.; Sundberg, C. J.; Wengström, Y.; Rundqvist, H. Highly favorable physiological responses to concurrent resistance and high-intensity interval training during chemotherapy: the OptiTrain breast cancer trial. Breast cancer research and Treatment. Vol. 169. Núm. 1. p. 93-103. 2018.

-Naczk, A.; Huzarski, T.; Doś, J.; Górska-Doś, M.; Gramza, P.; Gajewska, E.; Naczk, M. Impact of Inertial Training on Muscle Strength and Quality of Life in Breast Cancer Survivors. International Journal of Environmental Research and Public Health. Vol. 19. Num. 6. p. 3278. 2022.

-Paulo, T. R. S.; Rossi, F. E.; Viezel, J.; Tosello, G. T.; Seidinger, S. C.; Simões, R. R.; Freitas Junior, R.; Freitas Junior. I. F. The impact of an exercise program on quality of life in older breast cancer survivors undergoing aromatase inhibitor therapy: A randomized controlled trial. Health and Quality of Life Outcomes. Vol. 17. Num. 1. p. 1-12. 2019.

-Penttine, H.; Utriainen, M.; Kellokumpu-Lehtinen, P. L.; Raitanen, J.; Sievänen, H.; Nikander, R.; Blomqvist, C.; Huovinen, R.; Vehmanen, L.; Saarto, T.; Effectiveness of a 12-month exercise intervention on physical activity and quality of life of breast cancer survivors; five-year results of the BREX-study. In vivo. Vol. 33. Num. 3. p. 881-888. 2019.

-Pereira, A. L. S.; Souza, E. R.; Vieira, K. H. Avaliação da qualidade de vida e consumo alimentar de pacientes oncológicos. Revista Brasileira de Obesidade, Nutrição e Emagrecimento. São Paulo. Vol. 15. Num. 96. p. 861-870. 2021.

-Rock, C. L.; Thomson, C.; Gansler, T.; Gapstur, S. M.; McCullough, M. L.; Patel, A. V.; Andrews, K. S.; Bandera, E. V.; Spees, C. K.; Robien, K.; Hartman, S.; Sullivan, K.; Grant, B. L.; Hamilton, K. K.; Kushi, L. H.; Caan, B. J.; Kibbe, D.; Black, J. D.; Wiedt, T. L.; McMahon, C.; Sloan, K.; Doyle, C. American Cancer Society guideline for diet and physical activity for cancer prevention. CA: a cancer journal for clinicians. Vol. 70. Num. 4. p. 245-271. 2020.

-Rodrigues, B. G.; Lemos, A. P. C.; Rodrigues, A. R.; Domenciano, J. C. Influência da atividade física no prognóstico do câncer de mama-revisão bibliográfica. Revista HMJMA. Vol. 2. Num. 02. p. 51-56. 2020.

-Santos, W. D. N.; Vieira, A.; Lira, C. A. B.; Mota, J. F.; Gentil, P.; Freitas Júnior, R.; Batttaglini, C. L.; Bottaro, M.; Vieira, C. A. V. Once a week resistance training improves muscular strength in breast cancer survivors: a randomized controlled trial. Integrative cancer therapies. Vol. 18. p. 1534735419879748. 2019.

-Silva Santos, A. E.; M. Primo, M. G. S.; Oliveira, A. S. D. S. S.; Silva Brito, A. K.; Carvalho, M. D. C. Composição corporal, força muscular e sarcopenia em pacientes com câncer de mama: uma revisão integrativa. Revista Brasileira de Obesidade, Nutrição e Emagrecimento. São Paulo. Vol. 16. Num. 103. p. 720-730. 2022.

-Soriano-Maldonado, A.; Díez-Fernández, D. M.; Esteban-Simón, A.; Rodríguez-Pérez, M. A.; Artés-Rodríguez, E.; Casimiro-Artés, M. A.; Moreno-Martos, H.; Toro-de-Federico, A.; Hachem-Salas, N.; Bartholdy, C.; Henriksen, M.; Casimiro-Andújar, A. J. Effects of a 12-week supervised resistance training program, combined with home-based physical activity, on physical fitness and quality of life in female breast cancer survivors: the EFICAN randomized controlled trial. Journal of Cancer Survivorship. p. 1-15. 2022.

-Wang, L. F.; Eaglehouse, Y. L.; Poppenberg, J. T.; Brufsky, J.W.; Geramita, E. M.; Zhai, S.; Davis, K. K.; Gibbs, B. B.; Metz, J.; Londen, G.; J. V. Effects of a personal trainer-led exercise intervention on physical activity, physical function, and quality of life of breast cancer survivors. Breast Cancer. Vol. 28. Num. 3. p. 737-745. 2021.

Published
2023-12-22
How to Cite
Silva, L. O. da, Sousa, I. M. L. de, Paim, R. T. T., Bardalho Filho, A. W., & Linhares, J. J. (2023). What are the benefits of physical activity in patients with breast cancer on physical and psychological health? A systematic review of randomized clinical trials. Brazilian Journal of Obesity, Nutrition and Weight Loss, 17(109), 387-406. Retrieved from https://www.rbone.com.br/index.php/rbone/article/view/2254
Section
Scientific Articles - Original