Relationship between vitamin D deficit and obesity: An actual review
Abstract
Obesity is a multifactorial disease and is a risk factor for other diseases, such as vitamin D deficiency. There are several factors linking obesity with hypovitaminosis D. This study aims to review recent publications and expose the factors that relate to vitamin D deficiency with obesity. The search of the literature was conducted through the portal CAPES and were selected national and international articles between 2000 and 2014. The criteria for inclusion and exclusion were articles in other languages than Portuguese or English, articles that were not relevant to the criteria imposed, article with animal experiments, and articles published for over 14 years. The key words used were: obesity; vitamin D; Vitamin D deficiency, body composition -the search was conducted in Portuguese and English. Studies have shown that obese individuals have lower serum levels of vitamin D compared to non-obese individuals and identified several factors involved in this relationship, both directly, and indirectly. More studies are needed to clarify the mechanisms involved in obesity relationship with vitamin D deficiency and thus contribute positively to prevent and control these diseases.
References
-Al-Daghri, N.M.; Guerini, F.R.; Al-Attas, O.S.; Alokail, M.S.; Alkharfy, K.M. Vitamin D Receptor Gene Polymorphisms Are Associated with Obesity and Inflammosome Activity. PLoS ONE. Vol. 9. Núm. 7. 2014.
-Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica Diretrizes Brasileiras de Obesidade 2009/2010 / ABESO -Associação Brasileira para o Estudo da Obesidade e da Síndrome Metabólica. 3ª edição. 2009.
-Barchetta, I.; De Bernardinis, M.; Capoccia, D.; Baroni, M.G.; Fontana, M. Hypovitaminosis D is Independently Associated with Metabolic Syndrome in Obese Patients. PLoS ONE. Vol. 8. Núm. 7. 2013.
-Blum, M.; Dolnikowski, G.; Seyoum, E.; Susan, S.H. Vitamin (3) in fat tissue. Endocrine Reviews. Vol. 33. p. 90‐94. 2008.
-Brasil. Ministério da Saúde. Secretaria de Atenção à Saúde. Departamento de Atenção Básica. Obesidade. Brasília. Cadernos de Atenção Básica. Núm. 12. Série A. Normas e Manuais Técnicos. 2006.
-Brasil. Ministério da Saúde. PNDS 2006 -Pesquisa Nacional de Demografia e Saúde da Criança e da Mulher. Brasília. Relatório Final. 2008. Disponível em <http://bvsms.saude.gov.br/bvs/pnds/img/relatorio_final_pnds2006>. Acessado em 04/12/2014.
-Cheng, S.; e colaboradores. Adiposity, Cardiometabolic Risk, and Vitamin D Status: The Framingham Heart Study. Diabetes, Vol. 59. 2010.
-DeLuca, H.F. Overview of general physiologic features and functions of vitamin D. Am J Clin Nutr. p. 1689S-1696S. 2004.
-Dubois, L.; e colaboradores. Genetic and Environmental Contributions to Weight, Height, and BMI from Birth to 19 Years of Age: An International Study of Over 12,000 Twin Pairs. PLoS. Vol. 7. Núm. 2. 2012.
-Florez, H.; Martinez, R.; Chacra, W. Outdoor excercise reduces the risk of hypovitaminosis D in the obese. J Steroid Biochem Mol Biol. Vol. 103. p. 679-681. 2007.
-Grineva, E.N.; Karonova, T.; Micheeva, E.; Bel, Y.O.; Nikitina, I.L. Vitamin D deficiency is a risk factor for obesity and diabetes type 2 in women atlate reproductive age. AGING. Vol. 5. Núm. 7. 2013.
-Gunther, C.W.; Legowski, P.A.; Lyle, R.M.; W,C.M.; McCAbe, L.D.; Peacock, M.; Teegarden, D. Parathyroid hormone is associated with decreased fat mass in young healthy women. International Journal of Obesity. Vol. 30. p. 94‐99. 2006.
-Heaney, R.P.; Dowell, M.S.; Hale, C.A. Calcium absorption varies within the reference range for serum 25-hydroxyvitamin D. J Am Coll Nutr. Vol. 22. p. 142-146. 2003.
-Holick, M.F. Vitamin D deficiency. New England Journal of Medicine. Vol. 357. p. 266-81. 2007.
-Hypponen, E.; Power, C. Vitamin D status and glucose homeostasis in the 1958 British birth cohort: the role of obesity. Diabetes Care. Vol. 29. p. 2244-2246. 2006.
-Instituto Brasileiro de Geografia e Estatística. POF 2008-2009.Antropometria e estado nutricional de crianças, adolescentes e adultos no Brasil. 2010.
-Konradsen, S.; Ag, H.; Lindberg, F.; Hexeberg, S.; Jorde, R. Serum 1,25-dihydroxy vitamin D is inversely associated with body mass index. Eur J Nutr. Vol. 47. p. 87-91. 2008.
-Liu, S.; Song, Y.; Ford, E.S.; Manson, J.E.; Buring, J.E.; Ridker, P.M. Dietary calcium, vitamin D, andthe prevalence of metabolic syndrome in middle-aged and older U.S. women. Diabetes Care. Vol. 28. p. 2926-2932. 2005.
-Maeda, S. S.; e colaboradores. Recomendações para o diagnóstico e tratamento da hipovitaminose D. Arq Bras Endocrinol Metab. Vol. 58. Núm. 5. 2014.
-Mariath, A.B.; Grillo, L.P.; Silva, R.O.; Schimitz, P.; Campos, I.C.; Medina, J.R.P. Obesidade e fatores de risco para o desenvolvimento de doenças crônicas não transmissíveis entre usuários de unidade de alimentação e nutrição. Cad. Saúde Publica. 2007.
-Martins, D.; Wolf, M.; Pan, D.; Zadshir, A.; Tareen, N.; Thadhani, R.; Felsenfeld, A.; Levine, B.; Mehrotra, R.; Norris, K. Prevalence of cardiovascular risk factors and the serum levels of 25-hydroxyvitamin D in the United States: data from the Third National Health and Nutrition Examination Survey. Arch Intern Med. Vol. 167. p. 1159-1165. 2007.
-National Institutes of Health, National Heart, Lung and blood Institute. Clinical Guidelines on the Identification, Evaluation and treatment of overweight and obesity in Adults. 2000.
-Parikh, S.J.; Edelman, M.; Uwaifo, G.I.; Freedman, R.J.; Semega-Janneh, M.; Reynolds, J.; Yanovski, J.A. The relationship between obesity and serum 1,25-dihydroxy vitamin D concentrations in healthy adults. J Clin Endocri-nol Metab. Vol. 89. p. 1196-1199. 2004.
-Pepe, J.; Romagnoli, E.; Nofroni, I.; Pacitti, M.T.; De Geronimo, S.; Letizia, C.; Tonnarini, G.; Scarpiello, A.; D’Erasmo, E.; Minisola, S. Vitamin D status as a major factor determining the circulating level of parathyroid hormone: A study in normal subjects. Osteoporos is Int. Vol. 16. p. 805‐812. 2005.
-Popkin, B.M. Recent dynamics suggest selected countries catching up tp US obesity. Am J Clin Nutr. Vol. 91. p. 284S-288S. 2010.
-Prentice, A.; Goldberg, G.R.; Schoenmakers, I. Vitamin D across the lifecycle: physiology and biomarkers. Am J Clin Nutr. Vol. 88. p. 500S. 2008.
-Reis, J.P.; Muhlen, D.; Miller, E.D. Relationof 25‐Hydroxyvitamin D and parathyroid hormone levels with metabolic syndrome among US adults. Eur J Endocrinol. Vol. 159. p. 41‐48. 2008.
-Schuch, N.J.; Garcia, V.C.; Martini, L.A. Vitamin D and endocrine diseases. Arq Bras Endocrinol Metabol. Vol. 53. p. 625-633. 2009.
-Shils, M.E.; Olson, J.A.; Shike, M.; Ross, A.C. Tratado de nutrição moderna na saúde e na doença. 9ª edição. Manole. Vol. 2. p. 1493-1500. 2003.
-Sun, X.; Zemel, M.B. 1 Alpha,25 hihydroxyvitamin D and corticosteroid regulate adipocyte nuclear vitamin D receptor. Int J Obes (Lond). Vol. 32. p. 1305‐1311. 2008.
-Targher, G.; Bertolini, L.; Scala, L. Associations between serum 25-hydroxyvitamin D3 concentrations and liver histology in patients with non-alcoholic fatty liver disease. Nutr Metab Cardiovasc Dis. Vol. 17. p. 517-524. 2007.
-World Health Orzanization. Obesity and overweight. Disponível em: <http://www.who.int/mediacentre/factsheets/fs311/en/>
-Ybarra, J.; Sánchez-Hernández, J.; Gich, I. Unchanged hypovitaminosis D and secondary hyperparathyroidism in morbid obesity after bariatric surgery. Obs Surg. Vol. 15. Núm. 3. p. 330-5. 2005.
-Ye, W.Z.; Reis, A.F.; Dubois-Laforgue, D.; Bellanne-Chantelot, C. Vitamin D receptor gene polymorphisms are associated with obesity in type 2 diabetic subjects with early age of onset. Eur J Endocrinol. Vol. 145. p. 181-186. 2001.
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