Intestinal dysbiosis and lifestyle of college students during the COVID-19 pandemic
Abstract
Intestinal dysbiosis is a condition of microbiota imbalance that favors the emergence of various pathologies. It occurs for different causes, including psychological stress, diet, physical inactivity and sleep deprivation. The object of this study is to relate the signs and symptoms of intestinal dysbiosis with the lifestyle of university students during the COVID-19 pandemic. This is a cross-sectional analytical study realized during the period from September to December 2022. There were used three instruments to collect data: a Sociodemographic Questionnaire, The Metabolic Trace Survey and Convid - Behavior Survey Questionnaire, they both adapted. 656 students participated, of which 52% reached a score indicative of food hypersensitivity. The average age was 21 years old and the sample was mostly female (79,2%). The results evidenced that, about the lifestyle of the group classified as dysbiosis, mostly reported having sleep problems during the pandemic. Furthermore, the sadness and depression symptoms, as well as anxiety and nervousness, had a high incidence. This data was also equivalent to the recurrence of the return to alcohol consumption and the high screen use among this group. It was also evidenced that there were no significant differences between the groups when analysed diet and physical activity. Therefore, it was concluded that the COVID-19 pandemic impacted the lives of students, favoring dysbiosis. So, adaptations in the university reality are interesting to achieve positive vitality and increase academic performance of this group.
References
-Alves, B.K.R.B.; Santos, L.C.; Sousa, P.V.L.; Santos, G.M.; Barros, N.V.A. Prevalência de sinais e sintomas sugestivos de disbiose intestinal em acadêmicos de uma instituição de ensino superior. Revista Brasileira de Obesidade, Nutrição e Emagrecimento. São Paulo. Vol. 14. Num. 87. 2020. p. 588-597.
http://www.rbone.com.br/index.php/rbone/article/view/1324
-Barros, M.B.A.; Lima, M.G.; Malta, D.C.; Szwarcwald, C.L.; Azevedo, R.C.S.; Souza Júnior, P.R.B.; Azevedo, L.O.; Machado, I.E.; Damacena, G.N.; Gomes, C.S.; Werneck, A.O.; Silva, D.R.P.; Pina, M.F.; Gracie, R. Relato de tristeza/depressão, nervosismo/ansiedade e problemas de sono na população adulta brasileira durante a pandemia de COVID-19. Epidemiologia e Serviços de Saúde. Vol. 29. Num. 4. 2020. p. e2020427. https://doi.org /10.1590/S1679-497420200004 00018
-Beam, A.; Clinger, E.; Hao, L. Effect of Diet and Dietary Components on the Composition of the Gut Microbiota. Nutrients. Vol. 13. Num. 8. 2021. p. 2795. https://doi.org/10.3390/ nu13082795
-Bishehsari, F.; Magno, E.; Swanson, G.; Desai, V.; Voigt, R. M.; Forsyth, C. B.; Keshavarzian, A. Alcohol and Gut-Derived Inflammation. Alcohol research: current reviews. Vol. 38. Num. 2. 2017. p. 163-171. https://www.ncbi. nlm.nih.gov/pmc/articles/PMC5513683/
-Carioni, M.L.; Araujo, M.C. Associação entre disbiose intestinal e o nível de ansiedade em estudantes da saúde de uma universidade da grande Florianópolis. Universidade do Sul de Santa Catarina. 2020. https://repositorio. animaeducacao.com.br/bitstream/ANIMA/9730/1/TCC_MariaLuisaCarioni.pdf
-Carvalho, A.F.M.; Sousa, G.G. The psychological effects of social distancing caused by the new Coronavirus in university students. Research, Society and Development. Vol. 10. Num. 8. 2021. p. e9710817245 https://rsdjournal.org/index.php/rsd/article/view/17245.
-Cordeiro, B.R.M.; Oliveira, R.S.B. Prevalência de disbiose intestinal e sua relação com doenças crônicas não transmissíveis em estudantes de uma Instituição de Ensino Superior de Fortaleza-CE. Revista Brasileira de Obesidade, Nutrição e Emagrecimento. São Paulo. Vol. 12. Num. 74. 2018. p. 767-775. http://www.rbone.com.br/index.php/rbone/article/view/790
-Costa, C.S.G. A importância da microbriota intestinal na saúde e em estados de disbiose: revisão narrativa. Universidade Fernando Pessoa. Porto. 2021. http://hdl.handle.net/ 10284/10461
-Cuevas-Sierra, A.; Milagro, F.I.; Aranaz, P.; Martínez, J.A.; Riezu-Boj, J.I. Gut Microbiota Differences According to Ultra-Processed Food Consumption in a Spanish Population. Nutrients. Vol. 13. Num. 8. 2021. p. 2710.
https://doi.org /10.3390/nu13082710
-Dantas, C.R.; Praxedes, M.C.; Medeiros, K.B. Análise do risco de Disbiose em professores de uma instituição privada de Natal-RN. Repositório Institucional do Centro Universitário do Rio Grande do Norte. 2021. http://repositorio.unirn.edu.br/jspui/handle/123456789/329
-Gundim, V.A.; Encarnação, J.P.; Santos, F.C.; Santos, J.E.; Vasconcellos, E.A.; Souza, R.C. de. Saúde mental de estudantes universitários durante a pandemia de covid-19. Revista Baiana de Enfermagem. Vol. 35. 2021.
-Halverson, T.; Alagiakrishnan, K. Gut microbes in neurocognitive and mental health disorders. Annals of Medicine. Vol. 52. Num. 8. 2020. p. 423-443. https://doi.org/10.1080/07853890. 2020.1808239
-Illiano, P.; Brambilla, R.; Parolini, C. The mutual interplay of gut microbiota, diet and human disease. The FEBS journal. Vol. 287. Num. 5. 2020. p. 833-855. https://doi.org/10.1111 /febs.15217
-Jacobine, T. A. Disbiose intestinal e nível de atividade física: um estudo com estudantes de Nutrição de um centro universitário no interior de Pernambuco. Universidade Federal de Pernambuco-UFPE. 2019. https://repositorio.ufpe.br/handle/123456789/33824
-Jasbi, P.; Mohr, A.E.; Shi, X.; Mahmood, T.; Zhu, Q.; Bruening, M.; Gu, H.; Whisner, C. Microbiome and metabolome profiles of high screen time in a cohort of healthy college students. Sci Rep. Vol. 12. Num. 3452. 2022.
https://doi.org/10.1038/s41598- 022-07381-3
-Liboredo, J.C.; Anastácio, L.R.; Ferreira, L.G.; Oliveira, L.A.; Della Lucia, C.M. Quarantine During COVID-19 Outbreak: Eating Behavior, Perceived Stress, and Their Independently Associated Factors in a Brazilian Sample. Front Nutr. Vol. 8. 2021. p. 704619. https://doi.org/ 10.3389/fnut.2021.7046.
-Matenchuk, B.A.; Mandhane, P.J.; Kozyrskyj, A. L. Sleep, circadian rhythm, and gut microbiota. Sleep medicine reviews. Vol. 53. 2020. p. 101340 https://doi.org/10.1016/j.smrv.2020. 101340
-Melo, B.R.C.; Oliveira R.S.B. Prevalência de disbiose intestinal e sua relação com doenças crônicas não transmissíveis em estudantes de uma Instituição de Ensino Superior de Fortaleza-CE. Revista Brasileira de Obesidade, Nutrição e Emagrecimento. São Paulo. Vol. 12. Num. 74. 2018. p. 767-775. http://www.rbone. com.br/index.php/rbone/article/view/790
-Melo, G.H.; Ribeiro, A.C.; Carneiro, N.S.; Melo Junior, G. de; Naves, J.S.; Araújo, V.A.; Oliveira Filho, R.M. Prevalência de sinais e sintomas de disbiose intestinal em estudantes do curso de medicina de uma instituição de ensino superior privada em Mineiros-GO. Ciências da saúde: teoria e prática. 2020. p. 123-133.
-Motiani, K.K.; Collado, M.C.; Eskelinen, J.J.; Virtanen, K.A.; Löyttyniemi, E.; Salminen, S. Nuutila, P.; Kalliokoski, K.K.; Hannukainen, J. C. Exercise Training Modulates Gut Microbiota Profile and Improves Endotoxemia. Med Sci Sports Exerc. Vol. 52. Num. 1. 2020. p. 94-104. https://doi.org/10.1249/MSS.0000000000002112
-Oliveira, N. Avaliação das mudanças no estilo de vida e consumo de alimentos de universitários durante a pandemia de covid-19. Revista da JOPIC. Vol. 7. Num. 11. 2021.
-Pantoja, C.L.; Costa, A.C.C.; Costa, P.L.S.; Andrade, M.A.H.; Silva, V.V.; Brito, A.P.S.O.; Garcia, H.C.R. Diagnóstico e tratamento da disbiose: Revisão Sistemática. Revista Eletrônica Acervo Saúde. Vol. Sup. 32. Num. 32. 2019. p. e1368. https://doi.org/10.25248/ reas.e1368.2019
-Pohl, K.; Moodley, P.; Dhanda, A.D. Alcohol's Impact on the Gut and Liver. Nutrients. Vol. 13. Num. 9. 2021. p. 3170. https://doi.org/10. 3390/nu13093170
-Redondo-Useros, N.; Nova, E.; González-Zancada, N.; Díaz, L.E.; Gómez-Martínez, S.; Marcos, A. Microbiota and Lifestyle: A Special Focus on Diet. Nutrients. Vol. 12. Num. 6. 2020. p. 1776. https://doi.org/10.3390/nu12061776
-Scarmozzino, F.; Visioli, F. Covid-19 and the Subsequent Lockdown Modified Dietary Habits of Almost Half the Population in an Italian Sample. Foods. Vol. 9. Num. 5. 2020. p. 675. https://doi.org/10.3390/foods9050675
-Sousa, A.R.; Alves, G.V.; Queiroz, A.M.; Florêncio, R. M. S.; Moreira, W. C.; Nóbrega, M.P.S.S.; e colaboradors. Men’s mental health in the COVID-19 pandemic: is there a mobilization of masculinities?. Rev Bras Enferm. Vol. 74. e20200915. 2021. https://doi.org/10.1590/0034-7167-2020-0915
-Souza, T.C.M.; Oliveira, L.A.; Daniel, M.M.; Ferreira, L.G.; Della Lucia, C.M.; Liboredo, J.C.; Anastácio, L.R. Lifestyle and eating habits before and during COVID-19 quarantine in Brazil. Public Health Nutrition. Vol. 25. Num. 1. 2022. p. 65-75.
-Stone, M.; Jones, D.S. The patient`s story; the cliinician`s thinking - A place to start. Institute for Functional Medicine. Textbook of functional medicine. 2005. p. 689-702.
-Tonini, I.G.O.; Vaz, D.S.S.; Mazur, C.E. Gut-brain axis: relationship between intestinal microbiota and mental disorders. Research, Society and Development. Vol. 9. Num. 7. 2020. p. e499974303, 2020. https://rsdjournal. org/index.php/rsd/article/view/4303
-Verma, H.; Phian, S.; Lakra, P.; Kaur, J.; Subudhi, S.; Lal, R.; Rawat, C.D. Human Gut Microbiota and Mental Health: Advancements and Challenges in Microbe-Based Therapeutic Interventions. Indian journal of microbiology. Vol. 60. Num. 4. 2020. p. 405-419. https://doi.org/10.1007/s12088-020-00898-z
-Zimmermann, L.; Cezar, T. Prevalência de sinais e sintomas avaliados em um grupo de emagrecimento de um centro universitário do oeste do paraná. Fag Journal of Health (FJH). Vol. 2. Num. 2. 2020. p. 284-292.
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